LOW-DOSE DOXYCYCLINE INHIBITS HYDROGEN PEROXIDE-INDUCED OXIDATIVE STRESS, MMP-2 UP-REGULATION AND CONTRACTILE DYSFUNCTION IN HUMAN SAPHENOUS VEIN GRAFTS

Low-dose doxycycline inhibits hydrogen peroxide-induced oxidative stress, MMP-2 up-regulation and contractile dysfunction in human saphenous vein grafts

Mazen Saeed,1 Mehmet Zuhuri Arun,2 Mehmet Guzeloglu,3 Ceylan Onursal,1 Goksel Gokce,2 Ceren Gonen Korkmaz,2 Buket Reel21Ege University, Faculty of Pharmacy, Department of Pharmacology, 35100 Bornova, Izmir, Turkey; 2Ege University, Faculty of Pharmacy, Department of Clinical Pharmacy, 35100 Bornova, Izmir, Turkey; 3Optimed Hospital, Department of C

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Development of the retinotectal system in the direct-developing frog Eleutherodactylus coqui in comparison with other anurans

Abstract Background Frogs primitively have a biphasic life history with an aquatic larva (tadpole) and a usually terrestrial adult.However, direct developing frogs of the genus Eleutherodactylus have lost a free living larval stage.Many larval structures never form during development of Eleutherodactylus, while limbs, spinal cord, and an adult-like

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